INIMINI-chip: immune- and microbiota-competent intestine-on-a-chip

INIMINI-chip: immune- and microbiota-competent intestine-on-a-chip

Organisatie-onderdeel

Overig

Projectcode

LWV20135

MMIP

Landbouw, Water, Voedsel>Sleuteltechnologieën LWV>Smart Technologies in Agri-Horti-Water-Food

Startdatum

01/01/21

Einddatum

31/12/24

Samenvatting

Gut-on-chips are the latest in vitro models to predict in vivo efficacy of food and nutraceuticals. To increase the physiological emulation by these models and their effectivity, the next developmental step is the inclusion of multiple compartments. Here, we set out to generate an immune- and microbiota-competent intestine-on-a-chip. This will yield a model that will reduce the need for animal testing, support development of healthy foods and improves in vitro risk and toxicological assessments.