Projecttitel: INIMINI-chip: immune- and microbiota-competent intestine-on-a-chipProjectnummer: LWV20.135Missie: SleuteltechnologieënMMIP: ST1 Smart technologies in agri-horti-water-food
Gut-on-chips are the latest in vitro models to predict in vivo efficacy of food and nutraceuticals. To increase the physiological emulation by these models and their effectivity, the next developmental step is the inclusion of multiple compartments. Here, we set out to generate an immune- and microbiota-competent intestine-on-a-chip. This will yield a model that will reduce the need for animal testing, support development of healthy foods and improves in vitro risk and toxicological assessments.